Cycle Sync
For the woman who feels like a different person the week before her period.
Your hormones cycle. Your supplement should too. Cycle Sync is the two-phase hormone support system formulated by an OB-GYN and Registered Dietitian, designed to match your body across every phase of your cycle.
- 90-Day Guarantee
- Free Shipping
- Cancel Anytime
Benefits
- A healthy menstrual cycle rhythm*
- Healthy estrogen and progesterone levels*
- The body's natural response to everyday stressors*
- Restful sleep, libido, and overall well-being*
- Smoother transitions between cycle phases*
- Well-being throughout the month*
Who This Is For
- You feel noticeably different, emotionally or physically, in the week before your period
- You've been told everything is 'normal' but it doesn't feel normal
- You want to trust your body again
- Motivation disappears mid-month
- You've tried general multivitamins and PMS supplements that did not move the needle
- You want hormonal support without synthetic hormones or prescription intervention
Do You Offer A Guarantee?
"I noticed a difference within the first two weeks. My mood felt more even and my cramps were noticeably lighter. I've tried a lot of supplements — this one actually works with my cycle."
You have tried generic vitamins. You have done the routines. Here is what they were missing.
When you take the same supplement every single day, you are giving your body nutrients it does not need right now, and missing the ones it actually does. That is not a willpower problem. That is a structure problem.
Cycle Sync was designed to fix exactly that.
Two phases. Two formulations. One body finally being supported the way it works.
We designed Cycle Sync to reflect the natural flow of estrogen and progesterone across the menstrual cycle. You will see below the shift from rising estrogen in Phase 1, to rising progesterone and breaking down estrogen in Phase 2. Mimicking this flow with the right ingredients will help you feel your best and support a healthy, consistent cycle.*
Menstruation + Follicular
Estrogen is rising
Your body is repairing and building.
The first half of your cycle begins with menstruation, then moves into the follicular phase as your body prepares for ovulation. Estrogen rises steadily throughout this window. Phase 1 is formulated to support iron stores, energy metabolism, and antioxidant pathways to match this biological phase.*
Ovulation + Luteal
Progesterone rises
Estrogen begins to break down.
After ovulation, progesterone takes the lead while estrogen begins to metabolize. This is when many women feel the most shift in mood, energy, and comfort. Phase 2 is formulated to support nervous system function, progesterone production, and estrogen metabolism during the second half of your month.*
Two bottles. Taken at the right time in your cycle. That is the system.
Clinically proven and trusted by practitioners around the country
“I use Cycle Sync in my practice because it supports women through every phase of their cycle. The formulations are high quality, research-backed, and reflect how I care for my patients. It’s also priced in a way that makes it accessible, which means my patients can actually stay consistent.”
Dr. O’Shell, OBGYN
Board-Certified OB/GYN
What happens in your first 90 days.
Weeks 1–3
The first signals.
Your body is adjusting to phase-based nutritional support. Many women begin to notice shifts in how they feel during different parts of their cycle. Sleep and stress patterns start to shift. These early signals tell you the structure is working.*
Weeks 4–7
The shift you have been waiting for.
This is where most women feel the difference. The cyclical pattern becomes clearer, mood becomes more stable week to week, and energy feels more consistent across the month.*
Weeks 8–12
The routine clicks.
By weeks 8 to 12, the structure becomes second nature. Your cycle tracking feels more predictable. Your routine is locked in. Your overall sense of wellbeing reflects the consistency you have built.*
12 clinically backed ingredients. Every one chosen for a reason.
Cycle Sync is not a general women's multivitamin. Every ingredient was selected for what your body needs at a specific point in your cycle, backed by published research, and formulated by practitioners who work with women's hormones every day.
Vitamin B6
P-5-P (active form)
50–100 mg
Pyridoxal-5-phosphate is the active form of vitamin B6. Research has examined B6's role in neurotransmitter synthesis and studies have measured mood-related outcomes during the premenstrual phase.
Boron
Boron Glycinate
3 mg
Boron is a trace mineral that has been studied for its relationship to mineral metabolism and steroid hormone concentrations. Research has measured changes in circulating estradiol and testosterone levels.
Zinc
Bisglycinate Chelate
15–25 mg
Zinc is an essential mineral involved in reproductive function. Studies have examined zinc status in relation to ovulatory patterns and research has measured menstrual discomfort scores in supplementation trials.
Vitamin C
Ascorbic Acid
500 mg
Vitamin C is an essential nutrient and antioxidant. Research has examined its relationship to reproductive hormone patterns and studies have measured progesterone concentrations during the luteal phase.
Vitamin E
Mixed Tocopherols
400–600 IU
Vitamin E is a fat-soluble antioxidant. Multiple randomized controlled trials have examined vitamin E supplementation, measuring progesterone levels, endometrial measurements, and menstrual discomfort scores.
Chaste Tree
Vitex — Standardized Fruit Extract
400–500 mg
Vitex agnus-castus has been studied for its interaction with prolactin pathways and luteinizing hormone. Research has examined its role in the luteal phase of the menstrual cycle. Multiple clinical trials have been published on this botanical.
NAC
N-Acetylcysteine
600 mg
N-Acetylcysteine has been studied in clinical trials examining ovulatory patterns and follicle-stimulating hormone and luteinizing hormone concentrations in women.
DIM
Diindolylmethane
150–200 mg
Diindolylmethane is a compound found in cruciferous vegetables. Research has examined its role in estrogen metabolism pathways, particularly the conversion of estradiol and the ratio of different hydroxyestrone metabolites.
Curcumin
With BioPerine®
500–1000 mg
Curcumin, the active compound in turmeric, has been studied for its anti-inflammatory pathways. Research includes trials measuring menstrual discomfort, as well as studies examining androgen and progesterone levels.
Calcium-D-Glucarate
CDG
500 mg
Calcium-D-Glucarate has been studied for its interaction with beta-glucuronidase enzyme activity and estrogen metabolism. Studies have measured changes in circulating estrogen levels.
Magnesium
Glycinate Form
300–400 mg
Magnesium is an essential mineral involved in over 300 enzymatic processes. Research has examined its relationship to hormone regulation and fluid balance across the menstrual cycle.
Ashwagandha
KSM-66® Extract
300–600 mg
Ashwagandha is an adaptogenic herb used in traditional Ayurvedic medicine. Randomized controlled trials have measured cortisol levels, stress markers, and quality of life outcomes in women.
The statements above describe findings from peer-reviewed research on individual ingredients in isolation. They are not claims about Cycle Sync. Study results vary based on dosage, population, and methodology.*
One supplement every day vs. the right support at the right time.
| Generic Daily Multi | Cycle Sync | |
|---|---|---|
| Phase-based nutrient timing across the cycle | ✗ | ✓ |
| Formulated by an OB-GYN and Registered Dietitian | ✗ | ✓ |
| Customized to your cycle timing | ✗ | ✓ |
| Accounts for estrogen and progesterone phases | ✗ | ✓ |
| Research-backed ingredient selection | ✗ | ✓ |
| Same formula 365 days a year | ✓ | ✗ |
Real women. Real cycles. Real results.
Individual results may vary. These statements reflect individual experiences and are not claims made by Rootify
What happens when your supplements actually match your cycle.*
Start your 90-day transformation.
Hormonal support is not a one-week fix. Most women feel the biggest shift between weeks 6 and 12. That is why we built the 90-day supply as our recommended starting point, and why we made it the best value.
30 Day Supply
$49.99
$44.99
Delivered every 30 days
~$1.50/day · Save 10%
- Satisfaction Guarantee
- Pause or cancel anytime
- Free shipping included
90 Day Supply
$149.99
$127.49
Delivered every 90 days
~$1.42/day · Save 15%
- Satisfaction Guarantee
- Pause or cancel anytime
- Free shipping included
180 Day Supply
$299.99
$239.99
Delivered every 180 days
~$1.33/day · Save 20%
- Satisfaction Guarantee
- Pause or cancel anytime
- Free shipping included
Free US shipping on all orders. 90-day money-back guarantee.
Frequently Asked Questions
-
Because hormones fluctuate between the follicular and luteal phase, we want to prime the right nutrients into the body to align with this fluctuation to set up for optimal balance.
-
Birth control and other hormonal contraceptives work by delivering synthetic hormones (like estrogen and progestin) to suppress ovulation and create changes in the cervix and uterine lining. Cycle Sync could interfere with or alter the intended effects of birth control, including decreasing its effectiveness in preventing pregnancy.
Therefore, the question to ask yourself is, why am I taking birth control? If it is for preventing pregnancy, Cycle Sync may not be your answer. But if the reason is something else, such as acne, painful periods, or hormone imbalance, it may be worth looking into trying to balance your hormones naturally instead with Cycle Sync. It does take time and effort, and should be under the supervision of a healthcare professional.
Have questions on this? Reach out to our team at hello@rootifysupplements.com for support!
-
If you are having a period, start Phase 1 on the first day of menstruation. Take Phase 1 for 15 days and phase 2 until next menstruation. It would be advised to track your cycle while taking this product for best results. Knowing your ovulation day will allow the proper time to transition between phases.
If you have not had a period for more than 3 months, it would be advised to contact your healthcare professional before starting Cycle Sync.
-
It is not suggested to take while pregnant. A prenatal should be taken during pregnancy and lactation. Cycle Sync is safe to take up until conception.
-
Yes, this can help alleviate estrogen dominance symptoms and help hormone production during perimenopause years.*
-
You should see improved symptoms within a couple weeks. However, it is suggested to take for at least 3 months before seeing changes in your menstrual cycle. The closer you can track your cycle to this product, the better the results. The product should also be accompanied by healthy habits such as proper hydration, daily movement, quality sleep, reducing stress, and an anti-inflammatory nutrition approach.*
-
It is suggested to take Cycle Sync with your first meal of the day. Taking without food may cause indigestion.
-
The use of this product should be consulted with a physician before using for those under the age of 18.
-
Hormone Tracking with Apps - The Natural Cycles app is compatible with Oura Ring, Apple Watch, and NC° Thermometers. The algorithm automatically syncs & analyzes your data for you. It can even monitor physical and emotional changes to spot patterns and get alerts for irregularities.
Hormone Tracking with Wearables - Devices like Tempdrop, Ava, or Oura track BBT, HRV, and sleep to estimate ovulation.
Basal Body Temperature (BBT) Method - Use a basal thermometer to measure body temperature every morning before getting out of bed. Before ovulation temperature is lower (97.0°F–97.7°F) and after ovulation progesterone causes a temperature rise (above 97.8°F). When there’s a half-degree rise in your temperature, you’re ovulating.
Calendar method - Track cycle length (from the first day of one period to the first day of the next). Subtract 14 days from your cycle length to give you an estimated ovulation day. For example, for an average 30 day cycle, your estimated ovulation date is Day 16. The more data you have on cycle length (multiple months worth), the more accurate the estimation. This method is likely to be the least accurate of those listed above.
-
Phase 1 includes menstruation and the follicular phase, while Phase 2 includes ovulation and the luteal phase. Therefore, on the day of ovulation, you will switch into Phase 2. Use the above tracking methods to correctly track your cycle. If unable to do so, take Phase 1 for 15 days, Phase 2 for 15 days.
-
This is where tracking your ovulation is very important, so you can still align the phases correctly. Some may experience a shorter or longer follicular phase, some may experience a shorter or longer luteal phase. By knowing your ovulation day, you know when to switch to the next phase. If your cycle is longer than 30 days, there may be a couple day gap between taking the next phase.
-
A proper cycle will help with fertility, so yes it can help regulate hormones for conception. In particular, this product helps solve progesterone insufficiency, which is a common cause of fertility issues. In addition, tracking your cycle will help you determine your ovulation day, which is very important for knowing what days you are most fertile.*
-
Yes, but it may not be as efficient. It will help lower inflammation and provide proper detoxification, but it will not necessarily help improve hormone levels to the same degree due to lower hormone production at this stage.*
-
We believe that this product is more effective when taken consistently in alignment with your menstrual cycle. By having a subscription, the product will constantly be at your door step to transition into that next month and keep you on track. This also allows you to customize the length of phases, as the bottle has 15 servings for each phase, but you can use next month’s supply to customize this for longer/shorter cycles.
-
It does not contain any synthetic hormones. All the ingredients are aimed to help aid in the natural production of hormones.
Your symptoms may be telling you something.
Take our 2-minute hormone quiz. Tell us what you have been experiencing throughout the month. We will show you what your symptoms may be pointing to.*
Take the Hormone Quiz*Quiz results are for informational purposes only and do not constitute medical advice.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare provider before starting any dietary supplement.